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Moreover, the KYN pathway, which is altered in both depression and CKD, has been implicated in gut permeability and immune dysregulation, further linking the gut-brain axis with kidney dysfunction (Kearns, 2024)

Baseline body weight and composition significantly impact resultsindividuals with higher starting weights may lose more absolute pounds but similar percentages compared to those with lower baseline weights

On the phospholipid membrane, more than 200 different structural and functional proteins, such as DGAT2, Rab18, perilipin and CCT, are located on the surface of LDs, regulating LD homeostasis and intracellular interactions [2][3]

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L.GibbsS.LangI.TorbickiA.et al (2016)